Takeshi Tsujino Selected Research

Triglycerides (Triacylglycerol)

7/2018	Impact of serum cholesterol esterification rates on the development of diabetes mellitus in a general population.
5/2011	Administration of angiotensin-converting enzyme inhibitors is associated with slow progression of mild aortic stenosis in Japanese patients.
2/2006	Chylomicron remnants stimulate release of interleukin-1beta by THP-1 cells.
4/2003	Bezafibrate improves hypertension and insulin sensitivity in humans.
4/2003	The renin-angiotensin system is involved in the production of plasminogen activator inhibitor type 1 by cultured endothelial cells in response to chylomicron remnants.
11/2002	Eicosapentaenoic acid improves endothelial function in hypertriglyceridemic subjects despite increased lipid oxidizability.

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Takeshi Tsujino Research Topics

Disease

16	Neoplasms (Cancer) 07/2018 - 03/2002
14	Hypertension (High Blood Pressure) 11/2023 - 05/2002
13	Pathologic Constriction (Stenosis) 10/2019 - 10/2006
13	Heart Failure 01/2018 - 01/2006
12	Anemia 12/2023 - 09/2008
11	Pancreatic Neoplasms (Pancreatic Cancer) 09/2011 - 05/2006
9	Pancreatitis 01/2014 - 03/2002
8	Diabetes Mellitus 01/2019 - 01/2006
8	Cholecystitis 01/2016 - 03/2002
7	Fibrosis (Cirrhosis) 11/2023 - 04/2007
6	Cardiovascular Diseases (Cardiovascular Disease) 03/2022 - 01/2008
6	Aortic Valve Stenosis (Aortic Stenosis) 09/2013 - 10/2010
6	Hypertrophy 06/2013 - 01/2008
6	Cholangitis 03/2013 - 11/2005
5	Hypoxia (Hypoxemia) 11/2023 - 03/2009
5	Biliary Tract Neoplasms (Biliary Tract Cancer) 04/2012 - 01/2009
5	Autoimmune Pancreatitis 11/2010 - 11/2003
5	Hypertriglyceridemia 04/2005 - 11/2002
4	Cardiomegaly (Heart Hypertrophy) 11/2023 - 01/2008
4	Left Ventricular Dysfunction 11/2016 - 04/2007
4	Gastric Outlet Obstruction 08/2014 - 04/2012
4	Chronic Renal Insufficiency 06/2013 - 01/2011
4	Hyperinsulinism (Hyperinsulinemia) 05/2009 - 01/2003
3	Proteinuria 01/2022 - 03/2011
3	Lymphatic Metastasis 12/2019 - 05/2008
3	Vascular Remodeling 01/2016 - 06/2013
3	Diastolic Heart Failure 07/2014 - 09/2007
3	Neoplasm Metastasis (Metastasis) 05/2012 - 08/2010
3	Gallbladder Neoplasms (Gallbladder Cancer) 05/2010 - 05/2006
3	Atherosclerosis 01/2010 - 04/2003
2	Disease Progression 12/2023 - 12/2019
2	Inflammation (Inflammations) 01/2022 - 02/2010
2	Edema (Dropsy) 01/2019 - 01/2007
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2018 - 07/2006
2	Iron Deficiencies 06/2015 - 09/2013
2	Type 2 Diabetes Mellitus (MODY) 09/2013 - 01/2010
2	Sclerosing Cholangitis 07/2010 - 05/2006
2	Hyperlipidemias (Hyperlipidemia) 07/2010 - 04/2003
2	Cholangiocarcinoma 05/2010 - 01/2008
2	Acute Cholecystitis 04/2009 - 04/2009
2	Bile Duct Neoplasms (Bile Duct Cancer) 05/2008 - 05/2006
2	Chronic Pancreatitis 12/2007 - 05/2006
2	Thiamine Deficiency 11/2007 - 01/2007
2	Beriberi 11/2007 - 01/2007
2	Systolic Heart Failure 09/2007 - 01/2006

Drug/Important Bio-Agent (IBA)

17	IronIBA 11/2023 - 03/2009
11	Gemcitabine FDA Link 04/2012 - 01/2008
9	SaltsIBA 11/2023 - 05/2002
9	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019 - 05/2007
6	PlasticsIBA 10/2019 - 05/2008
6	Triglycerides (Triacylglycerol)IBA 07/2018 - 11/2002
6	DiureticsIBA 07/2017 - 01/2006
5	MetalsIBA 10/2019 - 03/2002
5	Erythropoietin FDA Link 11/2017 - 03/2009
5	Interleukin-18 (Interleukin 18)IBA 10/2010 - 05/2003
4	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 07/2017 - 01/2007
4	Dietary IronIBA 12/2016 - 06/2013
4	urinastatin (MR 20)IBA 12/2013 - 04/2005
4	BezafibrateIBA 07/2010 - 01/2003
3	HDL CholesterolIBA 07/2018 - 05/2011
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 07/2014 - 01/2010
3	CytokinesIBA 03/2010 - 11/2005
3	CalciumIBA 07/2006 - 01/2003
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2022 - 03/2022
2	CholesterolIBA 07/2018 - 05/2013
2	Furosemide (Lasix)FDA LinkGeneric 07/2017 - 01/2012
2	azosemideIBA 07/2017 - 01/2012
2	Indicators and Reagents (Reagents)IBA 05/2017 - 01/2008
2	Amlodipine (Norvasc)FDA LinkGeneric 11/2016 - 03/2014
2	CollagenIBA 02/2016 - 04/2007
2	AldosteroneIBA 03/2014 - 09/2008
2	Amylases FDA Link 01/2014 - 10/2011
2	SteroidsIBA 01/2014 - 11/2003
2	Risperidone (Risperdal Consta)FDA LinkGeneric 12/2013 - 08/2013
2	Type 1 Angiotensin ReceptorIBA 09/2013 - 04/2007
2	Therapeutic UsesIBA 06/2013 - 01/2012
2	perfluoro- 2,2,2',2'- tetramethyl- 4,4'- bis(1,3- dioxolane)IBA 03/2013 - 05/2012
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 05/2011 - 01/2006
2	EnzymesIBA 05/2011 - 09/2002
2	HepcidinsIBA 04/2011 - 02/2010
2	S 1 (combination)IBA 04/2011 - 05/2010
2	Contrast MediaIBA 01/2011 - 01/2010
2	C-Reactive ProteinIBA 08/2010 - 03/2010
2	Interleukin-6 (Interleukin 6)IBA 03/2010 - 02/2010
2	rho-Associated KinasesIBA 01/2010 - 01/2008
2	Biomarkers (Surrogate Marker)IBA 09/2008 - 11/2005
2	Thiamine (Aneurin)FDA Link 11/2007 - 01/2007
2	Protease Inhibitors (Protease Inhibitor)IBA 07/2007 - 04/2005

Therapy/Procedure

24	Stents 10/2019 - 03/2002
11	Therapeutics 01/2021 - 11/2003
8	Drug Therapy (Chemotherapy) 12/2019 - 01/2009
6	Liver Transplantation 10/2019 - 07/2007
6	Self Expandable Metallic Stents 08/2014 - 05/2008
4	Catheters 03/2013 - 10/2006
3	Cholecystectomy 01/2016 - 04/2009
3	Combination Drug Therapy (Combination Chemotherapy) 12/2011 - 01/2009
2	Surgical Instruments (Clip) 12/2016 - 03/2011
2	Endoscopic Sphincterotomy 01/2016 - 01/2011
2	Radiotherapy 05/2012 - 01/2007
2	Gastrectomy 01/2010 - 01/2007